Metastatic Brain Tumors

  • Overall the most common brain tumors are metastatic brain tumors which arise from a primary tumor elsewhere in the body.
  • The distribution of metastatic tumor types in the brain reflects the distribution of systemic tumors in the general population
  • Therefore, most brain metastases arise from lung cancer, breast cancer, or  melanoma, which represent the three most common sites of primary tumors.
  • The number and location of metastases guides the determination of the proper treatment approach, especially the decision for surgical resection.
  • A major predictor of survival is the number of cranial lesions that occur in patients who present with metastatic brain disease.

Metastatic Tumor Case Presentation:

  • 65-year-old right handed lady with the history of metastatic ovarian cancer who presented with dysarthria and difficulty with bringing the right word out (anomia).
  • Her condition rapidly evolved  into inablility in moving her right arm and leg, and speak (aphasia, and right hemiparesis) and she was brought to the emergency room.
  • Although patient could understand spoken language, she was unable to express herself (expressive aphasia).
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